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The triangles and circles in Panel A represent censored data. Patients in the elotuzumab group received the following medications 45 to 90 minutes before each dose of elotuzumab: diphenhydramine at a dose of 25 to 50 mg or equivalent, ranitidine at a dose of 50 mg or equivalent, and acetaminophen at a dose of 650 to 1000 mg.The primary end point was investigator-assessed progression-free survival, which was defined as the time from randomization to the first occurrence of disease progression (not including clinical deterioration) or death from any cause, whichever occurred first. The overall response rate was 53% in the elotuzumab group as compared with 26% in the control group (odds ratio, 3.25; 95% CI, 1.49 to 7.11). FIND OUT MORE. Autodesk has resources for educators, students, parents, and professionals to support remote learning opportunities. The International Staging System (ISS) consists of three stages, with higher stages indicating more severe disease: stage I, serum β,The median investigator-assessed progression-free survival was 10.3 months (95% confidence interval [CI], 5.6 to not reached) in the elotuzumab group and 4.7 months (95% CI, 2.8 to 7.2) in the control group. PVC is one of the most widely used plastics in the world with a wide range of long-life applications such as window frames, pipes, flooring, cables, sport equipment, furniture and a range of lifesaving medical devices. global.affairs.aus a créé un design personnalisé sur 99designs. 1.3K likes. The triplet regimen of elotuzumab plus lenalidomide and dexamethasone is indicated for patients with multiple myeloma who have received at least one previous therapy.Pomalidomide, an immunomodulatory agent, has structural and mechanistic properties that are similar to those of lenalidomide, but it may also elicit distinct biologic effects.The combination of elotuzumab and pomalidomide may have synergistic clinical effects in patients with multiple myeloma that relapsed after treatment with lenalidomide or is refractory to lenalidomide. The analysis was based on the intention-to-treat population, which included all patients who underwent randomization. Vous pouvez en savoir plus sur les pads angulaires dans notre wiki Longboard. The previously reported safety profile of this regimen was confirmed and was similar to that of pomalidomide and dexamethasone alone.Supported by Bristol-Myers Squibb and AbbVie Biotherapeutics.We thank the patients, their families, and the investigators at each trial site; and Laura Yee of Caudex, New York, for professional medical writing assistance, including preparation of the first draft of the manuscript, funded by Bristol-Myers Squibb.From the National and Kapodistrian University of Athens, Athens (M.A.D. All rights are with Business Keeper AG./assets/flags/icon-italian-40d8c7537fdd193bdd60b77d07363b9077da9ea1df6f67c0efe318811afe48bd.svg#icon-italian,/assets/flags/icon-french-09eec298103c0a3301eec8d8890c06f53b3ba4b23868a6fc4b02c4c274070271.svg#icon-french,/assets/flags/icon-spanish-b7d8e4d8335bd6ea3de4764e48a99f7e4f789bc4eea6e7f3646863186d9d27eb.svg#icon-spanish,/assets/flags/icon-portuguese-a1c29935402b36fe980b83730788a81888d19c04bd563f2a62aa6fcadf2e59d8.svg#icon-portuguese,/assets/flags/icon-polish-1a65a06983b52b3f2944f9ce54eeb38835baafa002eff0d7b9baa593692594cc.svg#icon-polish,/assets/flags/icon-russian-ab82de6a94c17ecd103a24e52455dac5fb6d33db3b13931de72eacb6092993dc.svg#icon-russian,/assets/flags/icon-czech-c3131195a4cd908a2f74773722abde3a8f1353ddb403736ddbc3c9a6dd7c6bb8.svg#icon-czech,/assets/flags/icon-arabic-db2850e89c71821297cdcf0e1e2af538544101307ef483eb7bc5cee09d4a8398.svg#icon-arabic,/assets/flags/icon-chinese-84857bb8ebdce7d0ae7aa604360fb13e0cd0738969b4da9ae9aea51ad4ae77d3.svg#icon-chinese,/assets/flags/icon-japanese-241964bc6a975eb846faed0bcc9c416426fb5c352dd5b05409c54c5170a4aa9a.svg#icon-japanese,/assets/flags/icon-korean-4e9459b5d9e65a4a172b967f898f5fba4d9fc8bf53f1c8a58a7b1d7397a984dc.svg#icon-korean.We adhere without compromise to laws and regulations.We do not tolerate illegal or immoral practices, neither within our own company or on the part of our business partners.We do not tolerate conduct on the part of our employees that jeopardizes our company's good reputation.We are open and fair in our dealings with our employees and business partners.We distance ourselves from unfair competitive practices, and wish to succeed in the market by offering excellent products and services and competing fairly. You can learn more about The English Simmer by visiting her website. — both in France; National Hospital Organization Disaster Medical Center (N.T.) With boutique accommodations, exceptional amenities and stunning ocean views, Tally Ho Inn is the place to stay in Carmel-by-the-Sea, California. Furthermore, the progression-free survival results, as assessed by the investigators, were confirmed by blinded, independent central review. In addition, the Bavarian authorities have set up corona test centers for arriving passengers at Munich Airport.The Munich Airport Group (FMG) is committed to the principles of good and responsible corporate management. The trial was conducted in accordance with International Conference on Harmonisation Good Clinical Practice guidelines. Endless movies and TV shows. The overall response rate was higher in the elotuzumab group (53%; 95% CI, 40 to 66) than in the control group (26%; 95% CI, 16 to 40), with an odds ratio of 3.25 (95% CI, 1.49 to 7.11) (.Shown are the results of the Kaplan–Meier analysis of overall survival in all patients who underwent randomization. Contact us . ), and Silesian Medical University, Katowice (S.G.) — both in Poland; University Hospital, Nantes (P.M.), and Centre Hospitalier Universitaire de Poitiers–La Milétrie, Poitiers (X.L.) Always ad free. ); Heidelberg University Hospital, Heidelberg, Germany (M.S.R. The immunomodulatory agent pomalidomide plus dexamethasone has been shown to be effective in patients with multiple myeloma that is refractory to lenalidomide and a proteasome inhibitor.Patients with multiple myeloma that was refractory or relapsed and refractory to lenalidomide and a proteasome inhibitor were randomly assigned to receive elotuzumab plus pomalidomide and dexamethasone (elotuzumab group) or pomalidomide and dexamethasone alone (control group). They are not selected or validated by us and can contain inappropriate terms or ideas. All the infusion reactions were grade 1 or 2, and all resolved.The findings from this randomized trial showed that the addition of the monoclonal antibody elotuzumab to pomalidomide and dexamethasone resulted in a significant improvement over pomalidomide and dexamethasone alone in treatment outcomes of relapsed or refractory multiple myeloma. In addition, all patients had multiple myeloma that was refractory to their last therapy. S2 in the,At the time of the database lock (February 2018), after a minimum follow-up period of 9.1 months, 40% of treated patients in the elotuzumab group, as compared with 20% in the control group, were continuing to receive the assigned treatment (Fig. The most common grade 3 or 4 adverse events were neutropenia (13% in the elotuzumab group vs. 27% in the control group), anemia (10% vs. 20%), and hyperglycemia (8% vs. 7%). This includes ensuring legal and ethical conduct on the part of all managers and employees.When granting contracts and conducting calls to tenders, FMG requires bidders to sign a statement of commitment to take all necessary measures to avoid corruption. These clinical data confirm the findings of preclinical studies in mice, which showed that elotuzumab, pomalidomide, and dexamethasone synergize to kill myeloma cells (Fig. ); Dana–Farber Cancer Institute, Boston (P.G.R. Power your merchandising to the next level. Patients had received two or more previous lines of therapy, including at least two consecutive cycles of lenalidomide and a proteasome inhibitor alone or in combination. en savoir plus. Munich Airport has implemented numerous hygiene measures to ensure that passengers and guests can travel safely and have a comfortable stay during these times. Rude or colloquial translations are usually marked in red or orange. From new releases, to your favorite classics, and exclusive Originals, there's always something new to discover. Learn more.Architecture, Engineering and Construction,Software installation, registration & licensing. Sign in. Vous pouvez en savoir plus sur The English Simmer en visitant son site Web. One patient in the control group had a second primary cancer (grade 4 invasive breast carcinoma) that resulted in discontinuation of treatment. Whether you are looking for quality online instruction that can be seamlessly integrated into your curriculum, or self-paced courses or projects to supplement classwork, we’ve got you covered. Learn best practices, ask questions, and collaborate with your peers.Ask Autodesk Experts about working remotely and collaboration with our products during Community Office Hours, every Tuesday. © 2013-2020 Reverso Technologies Inc. All rights reserved.These examples may contain rude words based on your search.These examples may contain colloquial words based on your search.Il donne aussi l'occasion aux candidats d',It is also an opportunity for candidates to,I found it very insightful and would love to,Lisez la spécification Rack si vous souhaitez,Check out the Rack specification if you want to,Drew était un pêcheur passionné qui cherchent à,Au dernier atelier, de nombreux participants ont dit souhaiter,At the end of the final workshop, many participants said they hoped to.Examples are used only to help you translate the word or expression searched in various contexts. You can find out more about angled riser pads in our longboard wiki. From new releases, to your favorite classics, and exclusive Originals, there's always something new to discover.A growing selection of new TV shows and movies from the master storytellers at Disney, Pixar, Marvel, Star Wars, and National Geographic. We have redirected you to an equivalent page on your local site where you can see local pricing and promotions and purchase online.Autodesk has resources for educators, students, parents, and professionals to support remote learning opportunities. Le client a obtenu des dizaines d'idées uniques de designers professionnels et a choisi son design préféré. This includes ensuring legal and ethical conduct on … The most common treatment-related adverse events were neutropenia (18% in the elotuzumab group vs. 20% in the control group), hyperglycemia (18% vs. 11%), and anemia (10% vs. 15%) (Table S2 in the.Adverse events that led to discontinuation of treatment occurred in 18% of the patients in the elotuzumab group and in 24% of the patients in the control group; infections led to discontinuation in 7% of the patients in the elotuzumab group and in 5% in the control group. VinylPlus® is the voluntary commitment to sustainable development of the European PVC industry, working to improve the sustainability performance of PVC. Join the European PVC industry in the journey towards the sustainable use of PVC,Incineration with energy recovery and material recovery.#VSF2020 Goes Virtual - Registration OPEN!The VinylPlus® Product Label Recognised as a Label for Sustainable Public Purchasing in Belgium,VinylPlus®: Steering the PVC Industry Towards the Circular Economy,The VinylPlus Sustainability Forum 2020 Goes Virtual,VinylPlus - Committed to Sustainable Development,Highlights from the VinylPlus Sustainability Forum 2019. Loading... Save. S4 in the,Adverse events of any cause that were reported in at least 10% of the patients in either treatment group and adverse events of special interest are shown in,The incidence of serious adverse events was 53% in the elotuzumab group and 55% in the control group. En Savoir Plus conseille, sensibilise et forme tout type de public, afin d’agir pour un développement durable. The hazard ratio for disease progression or death was 0.54 (95% CI, 0.34 to 0.86; P=0.008), which represents a risk of progression or death that was 46% lower in the elotuzumab group than in the control group (,The progression-free survival benefit of elotuzumab was consistently observed across key patient subgroups that were defined according to baseline characteristics, including patients whose disease was refractory to both lenalidomide and a proteasome inhibitor, patients who were assessed as having high-risk disease on the basis of International Myeloma Working Group criteria, and patients with at least one cytogenetic abnormality (chromosome 17p deletion, t[4;14] translocation, or t[14;16] translocation) or at least one of the aforementioned cytogenetic abnormalities or a high lactate dehydrogenase level (.The median progression-free survival in the overall population as assessed by the independent review committee was 10.3 months (95% CI, 6.5 to not reached) in the elotuzumab group and 4.7 months (95% CI, 2.8 to 7.6) in the control group; the hazard ratio for progression-free survival was 0.51 (95% CI, 0.32 to 0.82) in favor of the elotuzumab group. Because immunomodulatory drugs act through several mechanisms.Here, we report the results from ELOQUENT-3, a randomized trial in which we assessed the efficacy and safety of the monoclonal antibody elotuzumab plus pomalidomide and dexamethasone as compared with pomalidomide and dexamethasone alone in patients with refractory or relapsed and refractory multiple myeloma who had previously received treatment with lenalidomide and a proteasome inhibitor.This multicenter, randomized, open-label, phase 2 trial was designed by the sponsors (Bristol-Myers Squibb and AbbVie Biotherapeutics) and investigators. EN DE. En savoir plus CAD Printer; 3 videos; 1,679 views; Last updated on Feb 25, 2018; Play all Share. The primary end point was investigator-assessed progression-free survival.A total of 117 patients were randomly assigned to the elotuzumab group (60 patients) or the control group (57 patients). — all in Japan; Hôpital Maisonneuve-Rosemont, University of Montreal, Montreal (R.L. ); Karol Marcinkowski University of Medical Sciences, Poznań (D.D. Très bien, je veux en savoir plus sur ce gars. Sign in to YouTube. Eligible patients had multiple myeloma that was refractory (disease progressed while the patient was receiving treatment or within 60 days after treatment discontinuation) or relapsed and refractory (disease progressed within 6 months after treatment discontinuation after the patient had at least a partial response) to lenalidomide and a proteasome inhibitor. S1 in the.Prophylaxis against thromboembolism was required for all patients according to institutional guidelines or at the discretion of the investigator. BE CARRIED AWAY BY … Specifically, the Kaplan–Meier curves for progression-free survival showed early separation that was sustained over time, with a risk of progression or death that was 46% lower in the elotuzumab group than in the control group. It is also an opportunity for candidates to learn more about the position. A total of 65% of the patients in each group had infections. Widely regarded as the bike industry's leading innovator of game-changing technologies, Cannondale and its handcrafted bicycles continue to innovate across mountain, road, and electric bikes. Drew était un pêcheur passionné qui cherchent à en savoir plus sur la pêche basse. Key exclusion criteria were previous treatment with pomalidomide, active plasma-cell leukemia, and a creatinine clearance of less than 45 ml per minute. From Monday to Saturday 8.00 AM to 8.00 PM (Local time) Available languages: EN, IT, FR, DE, HU, GR, SP, PT, CZ, SK Available languages from January 2021: NL, PL, DA, SV, NO. It may neither be copied and / or altered for commercial or private purposes nor for the purpose of being passed on. Pomalidomide dose reductions occurred in 20% of the patients in each treatment group. Access content from each service separately. With hubstairs, create, manage, and publish 3D photorealistic visual content without any technical experience. (Funded by Bristol-Myers Squibb and AbbVie Biotherapeutics; ELOQUENT-3 ClinicalTrials.gov number.Despite the widespread use of immunomodulatory agents and proteasome inhibitors, relapsed or refractory multiple myeloma is common, in part because of clonal heterogeneity and genomic complexity.Therapies that combine agents with different mechanisms of action have improved outcomes in patients with relapsed or refractory multiple myeloma. Preliminary overall survival was estimated by the Kaplan–Meier method; a preliminary hazard ratio was estimated with the use of a stratified Cox proportional-hazards model, with treatment as the single covariate.Patients were enrolled from March 2016 through April 2017 at 43 sites in Europe, North America, Japan, and Australia. For more than 20 years, EPA's ENERGY STAR program has been America's resource for saving energy and protecting the environment. We would like to show you a description here but the site won’t allow us. The median duration of response was not reached (95% CI, 8.3 to not reached) in the elotuzumab group and was 8.3 months (95% CI, 4.6 to not reached) in the control group (Fig. S1 in the,Treatment was administered in 28-day cycles until disease progression, development of unacceptable toxic effects, or withdrawal of consent (Fig. and the Japanese Red Cross Medical Center (K.S. Learn more about our Customer Support contact numbers based on your current location. Elotuzumab dose reductions were not permitted, but dose delays occurred in 33% of the patients in the elotuzumab group.Shown are the results of the Kaplan–Meier analysis of the primary end point, progression-free survival, in all patients who underwent randomization (Panel A) and the results of an analysis of progression-free survival in subgroups defined according to baseline characteristics (Panel B). The hazard ratio for disease progression or death in the elotuzumab group as compared with the control group was 0.54 (95% confidence interval [CI], 0.34 to 0.86; P=0.008). 18+ only. Watch from 4 different devices at once.Bundle and save. Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Information, resources, and support needed to approach rotations - and life as a resident.Valuable tools for building a rewarding career in health care.Information and tools for librarians about site license offerings.The authorized source of trusted medical research and education for the Chinese-language medical community.The most trusted, influential source of new medical knowledge and clinical best practices in the world.Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma.Characteristics of the Patients at Baseline.Investigator-Assessed Treatment Response.Case Records of the Massachusetts General Hospital,Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer,One Step at a Time — Clinical Evidence that KRAS Is Indeed Druggable,Avelumab Maintenance Therapy for Advanced or Metastatic Urothelial Carcinoma,A Pandemic within a Pandemic — Intimate Partner Violence during Covid-19,Case 29-2020: A 66-Year-Old Man with Fever and Shortness of Breath after Liver Transplantation,Five-Year Analysis of Adjuvant Dabrafenib plus Trametinib in Stage III Melanoma,Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis,http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/003967/WC500206673.pdf,http://packageinserts.bms.com/pi/pi_empliciti.pdf,http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/002682/WC500147717.pdf,http://www.celgene.com/content/uploads/pomalyst-pi.pdf,https://www.janssenmd.com/pdf/darzalex/DARZALEX_PI.pdf.The content of this site is intended for health care professionals. Exploratory end points included the time to response, the duration of response, and safety (end points are described in detail in the,For the final analysis of progression-free survival, we calculated that 114 patients would have to undergo randomization and 71 events (disease progression or death) would have to occur to provide the trial with 85% power to detect a hazard ratio for disease progression or death of 0.57 in the elotuzumab group as compared with the control group, using a log-rank test with a two-sided experiment-wise alpha of 0.2 (additional details are provided in the.The overall response rate in the two groups (final analysis) was compared with the use of a Cochran–Mantel–Haenszel test and its corresponding estimate of treatment odds ratio. After a minimum follow-up period of 9.1 months, the median progression-free survival was 10.3 months in the elotuzumab group and 4.7 months in the control group. Concordance between investigator assessments and independent review committee assessments of progression-free survival was 85%.According to investigator assessments, 20% of the patients in the elotuzumab group and 9% in the control group had a very good partial response or better. The triplet regimen of elotuzumab plus lenalidomide and dexamethasone is indicated for patients with multiple myeloma who have received at least one previous therapy. Get the full Disney+ experience, plus your favorite TV episodes from Hulu (ad-supported), and exclusive shows and events from ESPN+.Get exclusive streaming access on Disney+ with Premier Access to. Watch as many times as you like with Premier Access and your $6.99/mo Disney+ subscription.The best of Disney, Pixar, Marvel, Star Wars, and National Geographic. Overall, 60 patients were randomly assigned to the elotuzumab group and 57 to the control group; all but 2 patients (both in the control group) received their assigned treatment (Fig. Installer Manual (for France only) EN. ENERGY STAR is the simple choice for energy efficiency. S5 in the.Therapies approved for patients with multiple myeloma that is refractory to lenalidomide and a proteasome inhibitor include pomalidomide and dexamethasone, daratumumab monotherapy, and daratumumab plus pomalidomide and dexamethasone.Elotuzumab plus pomalidomide and dexamethasone was associated with a rate of grade 3 or 4 adverse events (57%) that was similar to that observed with pomalidomide and dexamethasone alone (60%); no new safety signals were identified beyond the findings reported with other elotuzumab and pomalidomide regimens.This trial, which was specifically designed to detect a large treatment effect in a relatively small sample, showed a significant benefit of elotuzumab plus pomalidomide and dexamethasone with respect to the primary end point of progression-free survival. Includes Hulu (ad-supported) plan. Subject to terms of Disney+ and ESPN+ Subscriber Agreement.Watch before its release to all Disney+ subscribers on December 4, 2020. The,Eligible patients were 18 years of age or older and had measurable multiple myeloma and an Eastern Cooperative Oncology Group performance status score of 0 to 2 (on a 5-point scale, with higher numbers indicating greater disability). En Savoir Plus, Amiens. ), Tokyo, and Ibaraki Prefectural Central Hospital, Kasama (M.H.) ); Bristol-Myers Squibb, Princeton, NJ (M.P.M., Y.-M.J., S.G.S., M.R., B.R. In addition, the odds ratio for the overall response rate showed that patients in the elotuzumab group were 3.25 times as likely to have a response to treatment as patients in the control group. Explication: … No deaths in either group were considered by the investigators to be due to the trial medication.At the time of the database lock, a total of 816 infusions of elotuzumab had been administered; three infusion reactions had occurred (deafness, chest discomfort, and an unspecified infusion-related reaction occurred in one patient each). ); and Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra (IDISNA), Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Pamplona, Spain (J.S.-M.).Address reprint requests to Dr. Dimopoulos at the National and Kapodistrian University of Athens, Alexandra Hospital, 80 Vasilissis Sofias Ave., Athens 11528, Greece, or at,Tap into groundbreaking research and clinically relevant insights.Concise summaries and expert physician commentary that busy clinicians need to enhance patient care.The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams.NEW! Your browser does not support JavaScript or your JavaScript is disabled in your browser.Due to the global coronavirus pandemic, international air and travel traffic is currently still restricted. ASSEMBLE Plus is a consortium of 26 organisations from 16 countries operating under the umbrella of the European Marine Biological Resource Centre (EMBRC-ERIC). The best of Disney, Pixar, Marvel, Star Wars, and National Geographic. Please report examples to be edited or not to be displayed. Le CDP (anciennement Carbon Disclosure Project), organisation internationale à but non lucratif gérant la plus importante plateforme de reporting environnemental dédiée aux entreprises et aux villes, et Accenture ont collaboré à un rapport mesurant le niveau d’engagement des entreprises françaises et du Benelux en matière de réduction des émissions carbone. Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services.A list of investigators in this trial is provided in the.The immunostimulatory monoclonal antibody elotuzumab plus lenalidomide and dexamethasone has been shown to be effective in patients with relapsed or refractory multiple myeloma. The Munich Airport Group (FMG) is committed to the principles of good and responsible corporate management. Embedding on other websites must be authorized by the creator of this video. Secondary end points were the overall response rate (partial response or better), as assessed by the investigators, and overall survival. The triangles and circles represent censored data.Overall survival data were immature at the time of the analysis; however, a trend favoring the elotuzumab group was observed (hazard ratio for death, 0.62; 95% CI, 0.30 to 1.28) (,The median time to response was similar in the two groups: 2.0 months in the elotuzumab group and 1.9 months in the control group. Monthly administration of elotuzumab starting in cycle 3 was effective and provided a potentially more convenient dosing schedule for patients than the approved dosing schedule of every other week.In conclusion, among patients with multiple myeloma that was refractory or relapsed and refractory to lenalidomide and a proteasome inhibitor, the combination of elotuzumab plus pomalidomide and dexamethasone resulted in significantly longer progression-free survival and a higher overall response rate than pomalidomide and dexamethasone alone. VinylPlus® commits to recycle 900,000 tonnes of PVC a year by 2025 Read more,Become a VinylPlus partner today! Whether you are looking for quality online instruction that can be seamlessly integrated into your curriculum, or self-paced courses or projects to supplement classwork, we’ve got you covered.Select your area of focus and access a curated list of content to help you deliver quality online instruction.Access online courses, curriculum, and certification to help you engage remote students.Prepare your students with BIM skills through online learning materials.Find tutorials for beginners to the most advanced users.Find fun activities and access comprehensive tools that help you teach core skills in engaging ways.This free app for 3D design, electronics, and coding is web-based and easy to learn.Hands-on projects that make distance learning fun.Supplement your child’s school assignments or give them an activity to keep them engaged and learning.This web-based app is designed explicitly to serve the needs of self-directed beginners.Explore fun projects made for your curious maker.Develop new skills and earn industry recognized certifications to help you open new career opportunities.Distance learning does not mean you are on your own. Customer Support. Il donne aussi l'occasion aux candidats d' en savoir plus sur le poste. Infusion reactions occurred in 3 patients (5%) in the elotuzumab group.Among patients with multiple myeloma in whom treatment with lenalidomide and a proteasome inhibitor had failed, the risk of progression or death was significantly lower among those who received elotuzumab plus pomalidomide and dexamethasone than among those who received pomalidomide plus dexamethasone alone. S2 in the.A total of 55% of the patients in the elotuzumab group and 53% in the control group received at least 90% of the planned doses of pomalidomide. Further details regarding the inclusion and exclusion criteria can be found in the,Patients were randomly assigned, in a 1:1 ratio, to receive elotuzumab plus pomalidomide and dexamethasone (elotuzumab group) or pomalidomide and dexamethasone (control group) (Fig.
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